HOW MUCH YOU NEED TO EXPECT YOU'LL PAY FOR A GOOD PKRRATING

The activated enzyme then phosphorylates its key substrate, the translational initiation element eIF2α. The resulting translational arrest blocks viral replication. PKR belongs into a conserved loved ones of 4 protein kinases (PKR, PERK, GCN2, HRI) that all phosphorylate eIF2α in reaction to diverse stimuli12, triggering the built-in stress respo